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The common symptoms of sepsis are increased heart rate, fever, cold and clammy skin, shortness of breath or rapid breathing, confusion or disorientation. ... but any infection can cause sepsis ...
Assess the patient to determine if other signs and symptoms are present: flushed face, hot, dry skin, low output, concentrated urine, anorexia, constipation, diarrhea, or vomiting. Older children may complain of sore throat, headaches, aching, and nausea, as well as, other symptoms. [17] Pulse should be checked at distal and proximal sites.
Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.
Severe sepsis causes poor organ function or blood flow. [9] The presence of low blood pressure, high blood lactate, or low urine output may suggest poor blood flow. [9] Septic shock is low blood pressure due to sepsis that does not improve after fluid replacement. [9] Sepsis is caused by many organisms including bacteria, viruses, and fungi. [10]
Drugs such as pyridoxalated hemoglobin polyoxyethylene, which scavenge nitric oxide from the blood, have been investigated, [16] as well as methylene blue which may inhibit the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway which has been suggested to play a significant role in distributive shock.
Since the syndrome is due to the accumulation of chloramphenicol, the signs and symptoms are dose related. [10] According to Kasten's review published in the Mayo Clinic Proceedings, a serum concentration of more than 50 μg/mL is a warning sign, [10] while Hammett-Stabler and John states that the common therapeutics peak level is 10-20 μg/mL and is expected to achieve after 0.5-1.5 hours of ...
Pyaemia (or pyemia) is a type of sepsis that leads to widespread abscesses of a metastatic nature. [1] It is usually caused by the staphylococcus bacteria by pus-forming organisms in the blood. Apart from the distinctive abscesses, pyaemia exhibits the same symptoms as other forms of septicaemia.
Complications include dehydration, sepsis, pneumonia, and multiple organ failure. [2] The most common cause is certain medications such as lamotrigine, carbamazepine, allopurinol, sulfonamide antibiotics, and nevirapine. [2] Other causes can include infections such as Mycoplasma pneumoniae and cytomegalovirus or the cause may remain unknown.