Ads
related to: italian citrus bergamot side effects
Search results
Results From The WOW.Com Content Network
The bergamot is a citrus fruit native to southern Italy. Production is mostly limited to the Ionian Sea coastal areas of the province of Reggio di Calabria in Italy, to such an extent that it is a symbol of the entire city. Most of the bergamot comes from a short stretch of land there, where the temperature is favourable.
Bergamottin and dihydroxybergamottin are linear furanocoumarins functionalized with side chains derived from geraniol. They are inhibitors of some isoforms of the cytochrome P450 enzyme, in particular CYP3A4. [2] This prevents oxidative metabolism of certain drugs by the enzyme, resulting in an elevated concentration of drug in the bloodstream.
Bergapten (5-methoxypsoralen) is a naturally-occurring organic chemical compound produced by numerous plant species, especially from the carrot family Apiaceae and the citrus family Rutaceae. For example, bergapten has been extracted from 24 species of the genus Heracleum in the family Apiaceae.
The opening includes no less than four distinct citrus notes: bergamot, bitter orange, lemon, and mandarin orange. This eau de parfum is designed for both men and women, and it’s impressively ...
Furanocoumarins have other biological effects as well. For example, in humans, bergamottin and 6',7'-dihydroxybergamottin are responsible for the " grapefruit juice effect ", in which these furanocoumarins affect certain P450 liver and gut enzymes, such as the inhibition of CYP3A4 which either activates or deactivates many drugs, thus leading ...
Citrus-forward top notes include neroli (of course), bergamot, red mandarin, and galbanum, opening to a floral heart of cumin, jasmine, orange flower, and orris, and an earthy base of vetiver ...
Ad
related to: italian citrus bergamot side effects