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2. Pain ladder - Wikipedia

   en.wikipedia.org/wiki/Pain_ladder

   "Pain ladder", or analgesic ladder, was created by the World Health Organization (WHO) as a guideline for the use of drugs in the management of pain. Originally published in 1986 for the management of cancer pain , it is now widely used by medical professionals for the management of all types of pain .

3. Serotonin–norepinephrine reuptake inhibitor - Wikipedia

   en.wikipedia.org/wiki/Serotonin–norepinephrine...

   The drug is used to treat acute and chronic pain. It has shown effectiveness in the treatment of fibromyalgia, though it is not specifically approved for this purpose. The drug is also under investigation as an antidepressant and for the treatment of neuropathic pain. It is related in chemical structure to venlafaxine.

4. Serotonin–norepinephrine–dopamine reuptake inhibitor

   en.wikipedia.org/wiki/Serotonin–norepinephrine...

   In addition to post-treatment relapse, depressive symptoms can even recur in the course of long-term therapy (tachyphylaxis). Also, currently available antidepressants all elicit undesirable side-effects, and new agents should be divested of the distressing side-effects of both first and second-generation antidepressants. [6]

5. Pain management - Wikipedia

   en.wikipedia.org/wiki/Pain_management

   Treatment approaches to chronic pain include pharmacological measures, such as analgesics (pain killer drugs), antidepressants, and anticonvulsants; interventional procedures, physical therapy, physical exercise, application of ice or heat; and psychological measures, such as biofeedback and cognitive behavioral therapy.

6. Analgesic adjuvant - Wikipedia

   en.wikipedia.org/wiki/Analgesic_adjuvant

   An analgesic adjuvant is a medication that is typically used for indications other than pain control but provides control of pain in some painful diseases. This is often part of multimodal analgesia, where one of the intentions is to minimize the need for opioids. [1] [2] [3]

7. Noradrenergic and specific serotonergic antidepressant

   en.wikipedia.org/wiki/Noradrenergic_and_specific...

   Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.