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With time, fluoxetine and norfluoxetine inhibit their own metabolism, so fluoxetine elimination half-life increases from 1 to 3 days, after a single dose, to 4 to 6 days, after long-term use. [9] Similarly, the half-life of norfluoxetine is longer (16 days) after long-term use.
SSRIs (fluoxetine in particular) are preferred over other anti-depressants due to their acceptability, tolerability, and superior reduction of symptoms in short-term trials. Long-term efficacy remains poorly characterized. Similar recommendations apply to binge eating disorder. [37]
SSRIs are modern antidepressants often used as a first-line treatment for major depressive disorder. Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram ...
SSRIs (fluoxetine in particular) are preferred over other antidepressants due to their acceptability, tolerability, and superior reduction of symptoms in short-term trials. Long-term efficacy remains poorly characterized. Bupropion is not recommended for the treatment of eating disorders, due to an increased risk of seizure. [61]
Depending on the antidepressant, it can be safe to switch immediately (also called a “direct switch”) to a replacement. But when it comes to transitioning from Zoloft to Prozac, tapering is ...
Sold under the brand name Prozac, fluoxetine is approved for treating certain forms of anxiety, namely OCD and panic disorder. Healthcare professionals might also prescribe fluoxetine off-label ...
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