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  2. Acid lipase disease - Wikipedia

    en.wikipedia.org/wiki/Acid_lipase_disease

    In acid lipase disease the lysosomal acid lipase enzyme is either lacking or missing. In both CESD and Wolman's disease there is a mutation with in the LIPA gene , which maps to chromosome 10q23.2, has 10 exons and is approximately 45 kb in length, [ 5 ] that encodes for the lysosomal acid lipase enzyme. [ 1 ]

  3. Hepatic lipase - Wikipedia

    en.wikipedia.org/wiki/Hepatic_lipase

    Hepatic lipase (HL), also called hepatic triglyceride lipase (HTGL) or LIPC (for "lipase, hepatic"), is a form of lipase, catalyzing the hydrolysis of triacylglyceride. Hepatic lipase is coded by chromosome 15 and its gene is also often referred to as HTGL or LIPC . [ 5 ]

  4. Acute pancreatitis - Wikipedia

    en.wikipedia.org/wiki/Acute_pancreatitis

    If the lipase level is about 2.5 to 3 times that of amylase, it is an indication of pancreatitis due to alcohol. [14] Serum lipase is more sensitive and specific than serum amylase in the diagnosis of acute pancreatitis, and is the preferred test in the diagnosis. [15] [16]

  5. Lipase - Wikipedia

    en.wikipedia.org/wiki/Lipase

    In biochemistry, lipase (/ ˈ l aɪ p eɪ s, ˈ l aɪ p eɪ z / LY-payss, LY-payz) refers to a class of enzymes that catalyzes the hydrolysis of fats. Some lipases display broad substrate scope including esters of cholesterol , phospholipids , and of lipid-soluble vitamins [ 1 ] [ 2 ] and sphingomyelinases ; [ 3 ] however, these are usually ...

  6. Lysosomal acid lipase deficiency - Wikipedia

    en.wikipedia.org/wiki/Lysosomal_acid_lipase...

    An ultrasound examination shows an accumulation of chalky material (calcification) in the adrenal gland in about half of infants with LAL-D. [2] [4] Complications of LAL-D progress over time, eventually leading to life-threatening problems such as extremely low levels of circulating red blood cells (severe anemia), liver dysfunction or failure ...

  7. Lipoprotein lipase deficiency - Wikipedia

    en.wikipedia.org/wiki/Lipoprotein_lipase_deficiency

    Lipoprotein lipase deficiency is a genetic disorder in which a person has a defective gene for lipoprotein lipase, which leads to very high triglycerides, which in turn causes stomach pain and deposits of fat under the skin, and which can lead to problems with the pancreas and liver, which in turn can lead to diabetes.

  8. Researchers find higher levels of dangerous chemical than ...

    www.aol.com/news/researchers-higher-levels...

    The state of California, which has its own environmental health agency, also lists the chemical as “known to cause cancer and reproductive toxicity” in men and women.

  9. Hormone-sensitive lipase - Wikipedia

    en.wikipedia.org/wiki/Hormone-sensitive_lipase

    Hormone-sensitive lipase, which has 11-fold greater affinity for diglycerides than triglycerides, predominantly cleaves these diglycerides, forming 2-monoglyceride and a free fatty acid. [14] [15] HSL is activated when the body needs to mobilize energy stores, and so responds positively to catecholamines and ACTH. It is inhibited by insulin.