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Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents.
Acute tubular necrosis (ATN) involves damage to the tubules of the kidney, and can be a complication in individuals with cirrhosis, because of exposure to toxic medications or the development of decreased blood pressure. Because of the damage to the tubules, ATN affected kidneys usually are unable to maximally resorb sodium from the urine.
Out of five non-statin cholesterol-lowering drug classes, only cholesterol absorption inhibitors are found to reduce the risk of liver cancer, a new study has found. The link between liver cancer ...
Hepatocellular carcinoma (HCC [1]) is the most common type of primary liver cancer in adults and is currently the most common cause of death in people with cirrhosis. [2] HCC is the third leading cause of cancer-related deaths worldwide.
The symptoms of liver disease that may appear, though, include nausea, lack of appetite, discomfort on the right upper corner of the abdomen, generalized itching, dark urine and yellow ...
Pyrrolizidine alkaloidosis can result in damage to the liver, kidneys, heart, brain, smooth muscles, lungs, DNA, lesions all over the body, and could be a potential cause of cancer. [ 1 ] [ 2 ] Pyrrolizidine alkaloidosis is known by many other names such as "Pictou Disease" in Canada [ 3 ] and "Winton Disease" in New Zealand. [ 4 ]
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Acute liver failure is defined as "the rapid development of hepatocellular dysfunction, specifically coagulopathy and mental status changes (encephalopathy) in a patient without known prior liver disease". [23] page 1557
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