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Tetanus vaccine, also known as tetanus toxoid (TT), is a toxoid vaccine used to prevent tetanus. [2] During childhood, five doses are recommended, with a sixth given during adolescence. [2] After three doses, almost everyone is initially immune, [2] but additional doses every ten years are recommended to maintain immunity. [3]
It aims to protect newborn infants from becoming infected with pertussis by administering DTaP/Tdap (tetanus, diphtheria and acellular pertussis) booster vaccine to parents, family members and any individuals who would come into regular contact with the newborn infant. By vaccinating these individuals with a pertussis booster, a pool of persons ...
Tetanus immunoglobulin (TIG), [1] also called tetanus antibodies or tetanus antitoxin. [46] It can be given as intravenous therapy or by intramuscular injection. Antibiotic therapy to reduce toxin production. Metronidazole intravenous (IV) is a preferred treatment. [48] Benzodiazepines can be used to control muscle spasms.
Diphtheria and tetanus toxoids and whole-cell [10] pertussis (DTP; now also "DTwP" to differentiate from the broader class of triple-combination vaccines) [9] vaccination was licensed in 1949. [13] Since the introduction of the combination vaccine, there has been an extensive decline in the incidence of pertussis, or whooping cough, the disease ...
The 2006 edition of The Green book has 468 pages, divided generally into two parts, preceded by a contents page, acknowledgements and preface, and followed by two indexes, one of vaccines by proprietary name and the other of vaccines by common name.
Neonatal tetanus (trismus nascentium) is a form of generalised tetanus that occurs in newborns. Infants who have not acquired passive immunity from an immunized mother are at risk. It usually occurs through infection of the unhealed umbilical stump, particularly when the stump is cut with a non-sterile instrument.
[6] [1] Tetanospasmin ("tetanus toxin") is a potent toxin with an estimated lethal dose less than 2.5 nanograms per kilogram of body weight, and is responsible for the symptoms of tetanus. [6] [1] Tetanospasmin spreads via the lymphatic system and bloodstream throughout the body, where it is taken up into various parts of the nervous system. [6]
A hexavalent vaccine, or 6-in-1 vaccine, is a combination vaccine with six individual vaccines conjugated into one, intended to protect people from multiple diseases. [1] [9] The term usually refers to the children's vaccine that protects against diphtheria, tetanus, pertussis, poliomyelitis, haemophilus B, and hepatitis B, [1] [9] which is used in more than 90 countries around the world ...