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Roth's spots, also known as Litten spots or the Litten sign, [1] are non-specific red lesions with white or pale centres, seen on the retina of the eye and although traditionally associated with infective endocarditis, can occur in a number of other conditions including hypertension, diabetes, collagen vascular disease, extreme hypoxia, leukemia and HIV.
Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender. [3] Osler's nodes can also be seen in Systemic lupus erythematosus; Marantic endocarditis; Disseminated gonococcal infection; Distal to infected arterial ...
Brushfield spots are small, white or greyish/brown spots on the periphery of the iris in the human eye due to aggregation of connective tissue, a normal constituent of the iris stroma. The spots are named after the physician Thomas Brushfield , who first described them in his 1924 M.D. thesis.
A petechia (/ p ɪ ˈ t iː k i ə /; [1] pl.: petechiae) is a small red or purple spot (≤4 mm in diameter) that can appear on the skin, conjunctiva, retina, and mucous membranes which is caused by haemorrhage of capillaries. [2] [3] The word is derived from Italian petecchia 'freckle', of obscure origin. [1]
Purpura (/ ˈ p ɜːr p jʊər ə / [1]) is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. [2]
Some rosacea treatments such as Soolantra, which contains topical ivermectin, can improve rosacea symptoms. The gut-skin connection Much research is centered on better understanding the connection ...
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Rosacea is a long-term skin condition that typically affects the face. [2] [3] It results in redness, pimples, swelling, and small and superficial dilated blood vessels. [2] Often, the nose, cheeks, forehead, and chin are most involved. [3] A red, enlarged nose may occur in severe disease, a condition known as rhinophyma. [3]