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Gout was historically known as "the disease of kings" or "rich man's disease" [3] [8] and has been recognized since at least the time of the ancient Egyptians. [ 3 ] References
If you have frequent gout flares, gout associated with tophi, or joint damage, your provider may prescribe medication to lower uric acid levels. These can help prevent gout flares and further ...
Gout is a form of inflammatory arthritis characterized by recurrent attacks of a single red, tender, hot, and swollen joint. [ 1 ] [ 2 ] Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. [ 3 ]
Gout presenting as slight redness in the metatarsophalangeal joint of the big toe. Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases ...
Low uric acid (hypouricemia) can have numerous causes. Low dietary zinc intakes cause lower uric acid levels. This effect can be even more pronounced in women taking oral contraceptive medication. [61] Sevelamer, a drug indicated for prevention of hyperphosphataemia in people with chronic kidney failure, can significantly reduce serum uric acid ...
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [4] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
Dactylitis, or "sausage digit", a diffuse swelling of a solitary finger or toe, is a distinctive feature of reactive arthritis and other peripheral spondylarthritides but can also be seen in polyarticular gout and sarcoidosis. Mucocutaneous lesions can be present. Common findings include oral ulcers that come and go.
Colchicine is typically prescribed to mitigate or prevent the onset of gout, or its continuing symptoms and pain, using a low-dose prescription of 0.6 to 1.2 mg per day, or a high-dose amount of up to 4.8 mg in the first 6 hours of a gout episode.