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  2. Phospholipase A2 - Wikipedia

    en.wikipedia.org/wiki/Phospholipase_A2

    The enzyme phospholipase A 2 (EC 3.1.1.4, PLA 2, systematic name phosphatidylcholine 2-acylhydrolase) catalyses the cleavage of fatty acids in position 2 of phospholipids, hydrolyzing the bond between the second fatty acid "tail" and the glycerol molecule: phosphatidylcholine + H 2 O = 1-acylglycerophosphocholine + a carboxylate

  3. Phospholipid - Wikipedia

    en.wikipedia.org/wiki/Phospholipid

    Phospholipid synthesis occurs in the cytosolic side of ER membrane [16] that is studded with proteins that act in synthesis (GPAT and LPAAT acyl transferases, phosphatase and choline phosphotransferase) and allocation (flippase and floppase). Eventually a vesicle will bud off from the ER containing phospholipids destined for the cytoplasmic ...

  4. Lipoprotein-associated phospholipase A2 - Wikipedia

    en.wikipedia.org/wiki/Lipoprotein-associated_p...

    Lipoprotein-associated phospholipase A 2 (Lp-PLA 2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A 2 enzyme that in humans is encoded by the PLA2G7 gene. [5] [6] Lp-PLA 2 is a 45-kDa protein of 441 amino acids. [7] It is one of several PAF acetylhydrolases.

  5. Glycerophospholipid - Wikipedia

    en.wikipedia.org/wiki/Glycerophospholipid

    Glycerophospholipids are derived from glycerol-3-phosphate in a de novo pathway. [3] The term glycerophospholipid signifies any derivative of glycerophosphoric acid that contains at least one O-acyl, or O-alkyl, or O-alk-1'-enyl residue attached to the glycerol moiety. [4]

  6. Lipid bilayer - Wikipedia

    en.wikipedia.org/wiki/Lipid_bilayer

    The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules. These membranes form a continuous barrier around all cells . The cell membranes of almost all organisms and many viruses are made of a lipid bilayer, as are the nuclear membrane surrounding the cell nucleus , and membranes of the membrane ...

  7. Phospholipid scramblase - Wikipedia

    en.wikipedia.org/wiki/Phospholipid_scramblase

    Phospholipid scramblase 1 , a lipid-binding protein that enters the nucleus via the nonclassical NLS (257)GKISKHWTGI(266). The structure of the nuclear localisation sequence of scramblase PLSCR1 complexed to importin was determined using X-ray diffraction with a resolution of 2.20 Ångströms. [7] It is found in most mammals including humans.

  8. Phosphatidylethanolamine - Wikipedia

    en.wikipedia.org/wiki/Phosphatidylethanolamine

    [2] Phosphatidylethanolamines play a role in membrane fusion and in disassembly of the contractile ring during cytokinesis in cell division. [3] Additionally, it is thought that phosphatidylethanolamine regulates membrane curvature. Phosphatidylethanolamine is an important precursor, substrate, or donor in several biological pathways. [2]

  9. Flippase - Wikipedia

    en.wikipedia.org/wiki/Flippase

    Structure of a flippase, showing the two major subunits of the enzyme. Flippases are transmembrane lipid transporter proteins located in the cell membrane.They are responsible for aiding the movement of phospholipid molecules between the two layers, or leaflets, that compose the membrane (transverse diffusion, also known as a "flip-flop" transition).