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The α-crystallin family and βγ-crystallins compose the major family of proteins present in the crystalline lens. They occur in all vertebrate classes (though gamma-crystallins are low or absent in avian lenses); and delta-crystallin is found exclusively in reptiles and birds. [13] [14]
The lens is located towards the front part of the vertebrate eye, called the anterior segment, which includes the cornea and iris positioned in front of the lens. The lens is held in place by the suspensory ligaments (Zonule of Zinn), [1] attaching the lens at its equator to the rest of the eye [2] [3] through the ciliary body.
The lens is suspended to the ciliary body by the suspensory ligament (zonule of Zinn), made up of hundreds of fine transparent fibers which transmit muscular forces to change the shape of the lens for accommodation (focusing). The vitreous body is a clear substance composed of water and proteins, which give it a jelly-like and sticky composition.
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Aphakia correction: High degree hypermetropia due to absence of lens (aphakia) is best corrected using intraocular lens implantation. [ citation needed ] Refractive lens exchange (RLE): A variation of cataract surgery where the natural crystalline lens is replaced with an artificial intraocular lens ; the difference is the existence of abnormal ...
The eye's natural lens is usually replaced with an artificial intraocular lens (IOL) implant. [2] Over time, metabolic changes of the crystalline lens fibres lead to the development of a cataract, causing impairment or loss of vision. Some infants are born with congenital cataracts, and environmental factors may lead to cataract formation.
The refracting superposition eye has a gap between the lens and the rhabdom, and no side wall. Each lens takes light at an angle to its axis and reflects it to the same angle on the other side. The result is an image at half the radius of the eye, which is where the tips of the rhabdoms are.
The zonule of Zinn (/ ˈ t s ɪ n /) (Zinn's membrane, ciliary zonule) (after Johann Gottfried Zinn) is a ring of fibrous strands forming a zonule (little band) that connects the ciliary body with the crystalline lens of the eye. [1] The Zonular fibers a viscoelastic cables, although their component microfibrils are stiff structures.