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CHS is a paradoxical syndrome characterized by hyperemesis (persistent vomiting), as opposed to the better known antiemetic properties of cannabinoids. [15] The most prominent CHS symptoms are cyclical nausea, vomiting, and abdominal pain, concomitant with chronic cannabinoid use. [15]
Aprepitant has been identified as having strong potential in treating protracted vomiting episodes in individuals with cannabinoid hyperemesis syndrome. [25] This syndrome is characterized by nausea, cyclical vomiting, and cramping abdominal pain resulting from prolonged, frequent cannabis use.
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]
Hyperemesis gravidarum (HG) is a pregnancy complication that is characterized by severe nausea, vomiting, weight loss, and possibly dehydration. [1] Feeling faint may also occur. [ 2 ] It is considered a more severe form of morning sickness . [ 2 ]
It is commonly used postoperatively as an antiemetic. The antiemetic activity increases with increased dosing; however, side effects also increase, which often limits maximal dosing. [13] For moderate to severe morning sickness and hyperemesis gravidarum: In the UK, Promethazine is the drug of first choice.
Symptoms of hyperemesis gravidarum include extreme nausea and vomiting. Like Kate Middleton, this mom was hospitalized for it. I had hyperemesis gravidarum during both my pregnancies.
In the wake of a landmark new study on hyperemesis gravidarum, one woman shares her horrific experience. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290 ...
Some studies [15] and patient groups say that the use of cannabinoids derived from cannabis during chemotherapy greatly reduces the associated nausea and vomiting, and enables the patient to eat. Synthesized tetrahydrocannabinol (also one of the main active substances in marijuana) is marketed as Marinol and may be practical for this application.