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The FDA's approval is based on data from two trials involving 469 participants, in which Zepbound helped ease breathing difficulties in patients with moderate to severe obstructive sleep apnea.
(S,S)-(+)-Ethambutol is powerful and selective antitubercular drug.It is a typical example of an old drug that was introduced for clinical use in its unichiral form. . Ethambutol contains two constitutionally symmetrical chiral centers in its structure and exists in three stereoisomeric forms, the enantiomeric pair (+)-(S,S)- and (−)-(R,R)-ethambutol, along with the achiral stereoisomer called m
Diaphragm pacing (and even earlier as electrophrenic respiration [1] [2]) is the rhythmic application of electrical impulses to the diaphragm to provide artificial ventilatory support for respiratory failure or sleep apnea.
[1] [2] CPAP has been shown to be 100% effective at eliminating obstructive sleep apneas in the majority of people who use the therapy according to the recommendations of their physician. [1] In addition, a meta-analysis showed that CPAP therapy may reduce erectile dysfunction symptoms in male patients with obstructive sleep apnea. [3]
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Periodic breathing is clusters of breaths separated by intervals of apnea or near-apnea. As opposed to normal breathing which is usually regular, periodic breathing is defined as three or more episodes of central apnea lasting at least 4 seconds, separated by no more than 30 seconds of normal breathing. [1]