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RefSeq Functional Elements (RefSeqFE): It is focused on describing non-genic functional elements which are gene regulatory regions such as: enhancers, silencers, DNase I hypersensitive regions, DNA replication origins etc.). The current scope of this project is restricted to the human and mouse genomes.
The vertebrate Robo3/Rig1 homolog is a more distant relative of the Robo gene family, and is thought to play a distinct role in axonal guidance. [ 16 ] [ 29 ] Robo3/Rig1 is alternatively spliced to generate a protein that inhibits Robo1/2-mediated repulsion, effectively leading to the promotion of midline crossing. [ 23 ]
n/a Ensembl ENSG00000171943 n/a UniProt P0DJJ0 n/a RefSeq (mRNA) NM_001271872 NM_001329984 n/a RefSeq (protein) NP_001258801 NP_001316913 n/a Location (UCSC) Chr 1: 121.18 – 121.39 Mb n/a PubMed search n/a Wikidata View/Edit Human SLIT-ROBO Rho GTPase activating protein 2C is a protein in humans that is encoded by the SRGAP2C gene. Cortical development gene Slit-Robo Rho GTPase-activating ...
213541 Ensembl ENSG00000198492 ENSMUSG00000040025 UniProt Q9Y5A9 Q91YT7 RefSeq (mRNA) NM_016258 NM_001172828 NM_001173128 NM_145393 RefSeq (protein) NP_001166299 NP_001166599 NP_057342 NP_663368 Location (UCSC) Chr 1: 28.74 – 28.77 Mb Chr 4: 131.91 – 131.94 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse YTH N6-methyladenosine RNA binding protein 2 is a protein that in humans is ...
3207 15396 Ensembl ENSG00000005073 ENSMUSG00000038210 UniProt P31270 P31311 RefSeq (mRNA) NM_005523 NM_010450 RefSeq (protein) NP_005514 NP_034580 Location (UCSC) Chr 7: 27.18 – 27.19 Mb Chr 6: 52.22 – 52.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A11 is a protein that in humans is encoded by the HOXA11 gene. Function In vertebrates, the genes ...
Gene has been implemented at NCBI to characterize and organize the information about genes. It serves as a major node in the nexus of the genomic map, expression, sequence, protein function, structure, and homology data. A unique GeneID is assigned to each gene record that can be followed through revision cycles.
This program developed into a database of genes known as RefSeq and was released to the public in the Spring of 1999. By 2016, Pruitt managed a team of 22 scientists and worked closely with computer programmers and other teams who supported specific portions of the RefSeq data set.
The DCLRE1B/SNM1B/Apollo protein is a repair exonuclease that digests double-stranded and single-stranded DNA with a 5’ to 3’ directionality. [6]Using an SNM1B/Apollo knockout mouse model, evidence was obtained that SNM1B/Apollo protein is required to protect telomeres against illegitimate non-homologous end joining that can result in genomic instability and consequently in multi-organ ...