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Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; [2] it is a type of viral hepatitis. [6] During the initial infection period, people often have mild or no symptoms. [ 1 ]
The hepatitis C virus (HCV) [3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatocellular carcinoma , abbreviated HCC) and lymphomas in humans.
Although HCV was not discovered until April 1989, [3] an estimated 170 million people worldwide are infected by hepatitis C. [4] As of April 2014, 130—150 million globally suffer from chronic hepatitis C infection; a significant number develop cirrhosis of the liver or liver cancer. Each year, 350,000 to 500,000 people die from hepatitis C ...
Hepatitis C virus (HCV) can cause acute and chronic infections that are a major cause of hepatocellular carcinoma (HCC), advanced hepatic fibrosis and cirrhosis. [citation needed] HCC is a major cause of death in patients with chronic HCV infection. Regarding the pathogenesis of HCC associated with HCV, that virus may play direct or indirect roles.
Hepatitis C virus (HCV) genotypes refer to the genetic variations that occurs in the hepatitis C virus. Hepatitis C is a contagious disease that primarily affects the liver, causing severe damage as the disease progresses. [1] It is caused by the Hepatitis C virus, a small, enveloped RNA virus.
Hepatitis C virus (HCV), which is the causative agent of hepatitis C in humans, and a member of the species Hepacivirus C, was discovered in 1989. [5] Seven genotypes (1–7) and eighty-six subtypes (1a, 1b etc.) of hepatitis C virus have been named.
[166] [167] In a recent study by the WHO, the likelihood of being infected with hepatitis C virus was six times greater in those who also had HIV. [167] The prevalence of HIV-HCV co-infection worldwide was estimated to be 6.2% representing more than 2.2 million people. [167] Intravenous drug use was an independent risk factor for HCV infection ...
Infections of the hepatitis C virus (HCV) in children and pregnant women are less understood than those in other adults. Worldwide, the prevalence of HCV infection in pregnant women and children has been estimated to 1-8% and 0.05-5% respectively. [1]
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