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Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; [2] it is a type of viral hepatitis. [6] During the initial infection period, people often have mild or no symptoms. [ 1 ]
The hepatitis C virus (HCV) [3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. [4] [5]
What is Hepatitis C? In a nutshell, “hepatitis C is a virus that infects the liver, causing inflammation and scarring of the organ,” says K. V. Narayanan Menon, MD, the medical director of ...
Hepatitis D is a defective virus that requires hepatitis B to replicate and is only found with hepatitis B co-infection. [17] In adults, hepatitis B infection is most commonly self-limiting, with less than 5% progressing to chronic state, and 20 to 30% of those chronically infected developing cirrhosis or liver cancer. [ 30 ]
Hepatitis C virus (HCV) can cause acute and chronic infections that are a major cause of hepatocellular carcinoma (HCC), advanced hepatic fibrosis and cirrhosis. [ citation needed ] HCC is a major cause of death in patients with chronic HCV infection.
In all cases, the viral genotype of the HCV stays the same, occasionally mutations do occur making the treatment more complex by targeting the changes in the genotype. [7] Hepatitis C virus genotype is considered more common than the Hepatitis B virus infection contributing to more than a million cases annually [8] and is considered one of the ...
Although HCV was not discovered until April 1989, [3] an estimated 170 million people worldwide are infected by hepatitis C. [4] As of April 2014, 130—150 million globally suffer from chronic hepatitis C infection; a significant number develop cirrhosis of the liver or liver cancer. Each year, 350,000 to 500,000 people die from hepatitis C ...
Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) co-infection is a multi-faceted, chronic condition that significantly impacts public health.According to the World Health Organization (WHO), 2 to 15% of those infected with HIV are also affected by HCV, increasing their risk of morbidity and mortality due to accelerated liver disease.
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