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Pain is a distressing feeling often caused by intense or damaging stimuli. ... So far, dozens of types of nociceptor ion channels have been identified, and their ...
Explanatory model of chronic pain. Chronic pain is defined as reoccurring or persistent pain lasting more than 3 months. [1] The International Association for the Study of Pain (IASP) defines pain as "An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage". [2]
Pain can vary in intensity, from very mild to very severe; duration, short-lived to chronic; and location, one localized area or all over the body. [4] There are three different types of pain based on the duration of the sensations: acute, episodic, and chronic. The most common are acute and chronic.
The International Association for the Study of Pain (IASP) defines chronic pain as a general pain without biological value that sometimes continues even after the healing of the affected area; [8] [9] a type of pain that cannot be classified as acute pain [b] and lasts longer than expected to heal, or typically, pain that has been experienced on most days or daily for the past six months, is ...
' pain receptor ') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1] [2] [3] to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this process is called nociception.
There are different kinds or types of allodynia: Mechanical allodynia (also known as tactile allodynia) Static mechanical allodynia – pain in response when touched [2] Dynamic mechanical allodynia – pain in response to stroking lightly [3] Thermal (hot or cold) allodynia – pain from normally mild skin temperatures in the affected area
As long as humans have experienced pain, they have given explanations for its existence and sought soothing agents to dull or cease painful sensations.Archaeologists have uncovered clay tablets dating back as far as 5,000 BC which reference the cultivation and use of the opium poppy to bring joy and cease pain.
For moderate pain, tramadol, codeine, dihydrocodeine, and hydrocodone are used, with nicocodeine, ethylmorphine and propoxyphene or dextropropoxyphene (less commonly). Drugs of other types can be used to help opioids combat certain types of pain.