Search results
Results From The WOW.Com Content Network
Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene. [ 5 ] [ 6 ] CTCF is involved in many cellular processes, including transcriptional regulation , insulator activity, V(D)J recombination [ 7 ] and regulation of chromatin architecture.
CTCF molecules can form homodimers on DNA, which can be co-bound by cohesin; this chromatin loop structure helps constrain the ability of enhancers within the loop to target genes outside the loop. Loops with CTCF and cohesin at the start and end of the loop that restrict enhancer-gene targeting are "insulated neighborhoods."
CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. Transcriptional repressor CTCFL (this protein) is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a ...
Below the station embankment are four bus bays, while connected by two pedestrian bridges is the adjacent 1,120-space three level parking garage and overflow lot. East of the station is the additional 246-space surface parking lot, known as Lot A. Parking is free for patrons for either bus or light rail and is limited to 24 hours. Walkways from ...
200 South College [4] (formerly BB&T Center) is a 300-foot (91 m) high-rise in Charlotte, North Carolina. Completed in 1975, it consists of 22 floors and an 11-story parking garage . [ 5 ] On the second floor, it is connected to neighboring buildings via skybridges , as part of the Overstreet Mall .
University City Blvd is a light rail station on the LYNX Blue Line in Charlotte, North Carolina, United States. It is located on North Tryon Street and Periwinkle Hill Avenue in University City . The station consists of a single island platform in the street's median, connected to an adjacent parking garage by a pedestrian overpass.
Three Wells Fargo Center is a 450-foot (137 m) high rise in Charlotte, North Carolina. [1] Completed in 2000, the building consists of 32 floors with 890,000 square feet (83,000 m 2) of office space; it also includes an underground parking garage, an attached 10-story low-rise known as the Ratcliffe on the Green, and connects to Two Wells Fargo Center via skybridge, as part of the Overstreet Mall.
Two Wells Fargo Center is a 433-foot (132 m) high rise in Charlotte, North Carolina.Completed in 1971. [1] It is currently the 14th tallest building in Charlotte. The building consists of 32 floors, an atrium, plaza, seven-story parking garage, and is connected to neighboring buildings via skybridges, as part of the Overstreet Mall.