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  2. Drug delivery to the brain - Wikipedia

    en.wikipedia.org/wiki/Drug_delivery_to_the_brain

    The bloodbrain barrier is formed by special tight junctions between endothelial cells lining brain blood vessels. Blood vessels of all tissues contain this monolayer of endothelial cells, however only brain endothelial cells have tight junctions preventing passive diffusion of most substances into the brain tissue. [1]

  3. Blood–brain barrier - Wikipedia

    en.wikipedia.org/wiki/Bloodbrain_barrier

    The bloodbrain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [1]

  4. Ventricular system - Wikipedia

    en.wikipedia.org/wiki/Ventricular_system

    These form the ventricular system of the brain: [8] The neural stem cells of the developing brain, principally radial glial cells, line the developing ventricular system in a transient zone called the ventricular zone. [9] The prosencephalon divides into the telencephalon, which forms the cortex of the developed brain, and the diencephalon.

  5. Neurotransmitter - Wikipedia

    en.wikipedia.org/wiki/Neurotransmitter

    L-DOPA, a precursor of dopamine that crosses the bloodbrain barrier, is used in the treatment of Parkinson's disease. For depressed patients where low activity of the neurotransmitter norepinephrine is implicated, there is only little evidence for benefit of neurotransmitter precursor administration.

  6. List of regions in the human brain - Wikipedia

    en.wikipedia.org/wiki/List_of_regions_in_the...

    Brain at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (view tree for regions of the brain) BrainMaps.org; BrainInfo (University of Washington) "Brain Anatomy and How the Brain Works". Johns Hopkins Medicine. 14 July 2021. "Brain Map". Queensland Health. 12 July 2022.

  7. Human brain - Wikipedia

    en.wikipedia.org/wiki/Human_brain

    Long-chain fatty acids cannot cross the bloodbrain barrier, but the liver can break these down to produce ketone bodies. However, short-chain fatty acids (e.g., butyric acid, propionic acid, and acetic acid) and the medium-chain fatty acids, octanoic acid and heptanoic acid, can cross the bloodbrain barrier and be metabolised by brain cells.

  8. Cerebral circulation - Wikipedia

    en.wikipedia.org/wiki/Cerebral_circulation

    Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. [8] In an adult, CBF is typically 750 millilitres per minute or 15.8 ± 5.7% of the cardiac output. [9] This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute. [10] [11] [12]

  9. Blood barrier - Wikipedia

    en.wikipedia.org/wiki/Blood_barrier

    Blood barrier may refer to: Blood–air barrier; Bloodbrain barrier; Blood–ocular barrier; Blood–retinal barrier; Blood–testis barrier; Blood–thymus barrier;