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Retinoschisis is an eye disease characterized by the abnormal splitting of the retina's neurosensory layers, usually in the outer plexiform layer.Retinoschisis can be divided into degenerative forms which are very common and almost exclusively involve the peripheral retina and hereditary forms which are rare and involve the central retina and sometimes the peripheral retina.
Retinal detachment is a condition where the retina pulls away from the tissue underneath it. [1] [2] [3] It may start in a small area, but without quick treatment, it can spread across the entire retina, leading to serious vision loss and possibly blindness. [4] Retinal detachment is a medical emergency that requires surgery. [2] [3]
Retinoschisin also known as X-linked juvenile retinoschisis protein is a lectin [5] [6] that in humans is encoded by the RS1 gene. [7]It is a soluble, cell-surface protein that plays an important role in the maintenance of the retina where it is expressed and secreted by retinal bipolar cells and photoreceptors, [8] [9] as well as in the pineal gland. [10]
Rhegmatogenous retinal detachment (H33.1) Retinoschisis and retinal cysts — the retina separates into several layers and may detach Cyst of ora serrata; Parasitic cyst of retina NOS; Pseudocyst of retina Excludes: congenital retinoschisis (Q14.1) microcystoid degeneration of retina (H35.4) (H33.2) Serous retinal detachment Retinal detachment: NOS
Retinitis pigmentosa (RP) is a member of a group of genetic disorders called inherited retinal dystrophy (IRD) that cause loss of vision. [1] Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). [1]
The risk of retinal detachment is the greatest in the first 6 weeks following a vitreous detachment, but can occur over 3 months after the event.. The risk of retinal tears and detachment associated with vitreous detachment is higher in patients with myopic retinal degeneration, lattice degeneration, and a familial or personal history of previous retinal tears/detachment.
The causes of macular edema are numerous and different causes may be inter-related. It is commonly associated with diabetes.Chronic or uncontrolled diabetes type 2 can affect peripheral blood vessels including those of the retina which may leak fluid, blood and occasionally fats into the retina causing it to swell.
It is usually associated with disease processes in the retina, which involve the retina becoming starved of oxygen . The ischemic retina releases a variety of factors, the most important of which is vascular endothelial growth factor (VEGF). These factors stimulate the formation of new blood vessels (angiogenesis). These new vessels do not have ...