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U.S. Route 52 (US 52) is a major U.S. Highway in the Central United States that extends from the northern to southeastern region of the United States.Contrary to most other even-numbered U.S. Highways, US 52 primarily follows a northwest–southeast route, and it is signed north–south or east–west depending on the local orientation of the route.
U.S. Route 52 (US 52) runs east–west across the southern part of the state of Ohio along the Ohio River, passing through or very near the cities and towns of Cincinnati, Portsmouth, and Ironton. For its first 19 miles (31 km) or so, the highway runs concurrently with Interstate 74 (I-74) and I-75 before it winds through downtown Cincinnati ...
U.S. Route 52 (US 52) is a north–south United States highway that runs for 150 miles (240 km) from the South Carolina state line, near McFarlan, to the Virginia state line, near Mount Airy. It serves as a strategic highway through the central North Carolina Piedmont . [ 3 ]
U.S. Route 52 (US 52) is an east–west United States Numbered Highway that runs for 159.960-mile (257.431 km) from Charleston to the North Carolina state line near Cheraw. It serves as a strategic highway through the central part of the state.
U.S. Route 52 (US 52) skirts the western fringes of the U.S. state of West Virginia. It runs from the Virginia state line near Bluefield , where it is concurrent with Interstate 77 (I-77), in a general northwest and north direction to I-64 at Kenova .
U.S. Route 52 (US 52) in the state of Illinois is a surface road that traverses the north central and eastern portions of the state. It runs from the Dale Gardner Veterans Memorial Bridge over the Mississippi River between Sabula, Iowa, and Savanna with Illinois Route 64 (IL 64) southeast to the Indiana state line near Sheldon with US 24.
U.S. Route 52 Business is a special business route of U.S. Route 52 in Ironton, Ohio. U.S. Route 52 Business exits the mainline route at the village of Coal Grove , just south of Ironton then follows the original pre-1962 routing of U.S. 52 through the central business district of Ironton before rejoining the mainline near Hanging Rock .
U.S. Route 52 (US 52) in Virginia runs north–south through the southwestern part of the state along the Interstate 77 (I-77) corridor. Though an even-numbered U.S. route, it is signed north–south in Virginia (standard convention being to label even-numbered U.S. routes with east–west designations).