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Taurine (/ ˈ t ɔː r iː n /), or 2-aminoethanesulfonic acid, is a non-proteinogenic naturally occurring amino sulfonic acid that is widely distributed in animal tissues. [1] It is a major constituent of bile and can be found in the large intestine, and accounts for up to 0.1% of total human body weight.
In the decomposition of taurine, it has been shown that molecular oxygen is activated by Iron II, which lies in the coordinating complex of taurine dioxygenase. [2] Here the enzyme with conjunction of an Iron II and 2-oxoglutarate maintain non-covalent bonds by electrostatic interactions, and coordinate a nucleophilic attack from dioxygen on 2-oxoglutarate carbon number 2. [3]
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In enzymology, a taurine dehydrogenase (EC 1.4.99.2) is an enzyme that catalyzes the chemical reaction.. taurine + H 2 O + acceptor sulfoacetaldehyde + NH 3 + reduced acceptor. The 3 substrates of this enzyme are taurine, H 2 O, and acceptor, whereas its 3 products are sulfoacetaldehyde, NH 3, and reduced acceptor.
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Homotaurine (also known as tramiprosate (), 3-amino-1-propanesulfonic acid, or 3-APS) is a natural sulfonic acid found in seaweed. [3] It is analogous to taurine, but with an extra carbon in its chain.
Generic structure of a taurate. R is an odd numbered alkyl group C n H 2n+1 with n = 7 – 17 carbon atoms.. Taurates (or taurides) are a group of mild anionic surfactants.They are composed of a hydrophilic head group, consisting of N-methyltaurine (2-methylaminoethanesulfonic acid) and a lipophilic residue, consisting of a long-chain carboxylic acid (fatty acid), both linked via an amide bond.
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