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Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). [8] It is used either by mouth or injection into a muscle. [8] Hydroxyzine works by blocking the effects of histamine. [9]
Visceral pain is pain that results from the activation of nociceptors of the thoracic, pelvic, or abdominal viscera (organs). Visceral structures are highly sensitive to distension (stretch), ischemia and inflammation , but relatively insensitive to other stimuli that normally evoke pain such as cutting or burning.
Somatosensory amplification (SSA) is a tendency to perceive normal somatic and visceral sensations as being relatively intense, disturbing and noxious. It is a common feature of hypochondriasis and is commonly found with fibromyalgia, major depressive disorder, anxiety disorders, autism spectrum disorder, and alexithymia.
According to the Anxiety and Depression Association of America (ADAA), 6.8 million adults have GAD. Other anxiety disorders include obsessive-compulsive disorder, panic disorder, post-traumatic ...
Pain medications can cause paradoxical side effects, such as opioid-induced hyperalgesia (severe generalized pain caused by long-term opioid use). [ 107 ] [ 108 ] Sugar ( sucrose ) when taken by mouth reduces pain in newborn babies undergoing some medical procedures (a lancing of the heel, venipuncture , and intramuscular injections ).
Etifoxine, sold under the trade name Stresam among others, is a nonbenzodiazepine anxiolytic agent, primarily indicated for short-term management of adjustment disorder, specifically instances of situational depression accompanied by anxiety, such as stress-induced anxiety. [2] [6] Administration is by mouth. [7]