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What happens when aldosterone levels are low? Having lower-than-normal aldosterone levels is usually considered hypoaldosteronism, which is a condition characterized by a lack of (deficiency) or impaired function of aldosterone.
Symptoms of hypoaldosteronism, too little aldosterone, include low blood pressure, appetite loss, fatigue, and unexplained weight loss. Meanwhile, hyperaldosteronism (excessive aldosterone) may cause symptoms like high blood pressure and excessive sodium levels, combined with low potassium .
Low cortisol, low aldosterone, and high PRA suggests primary adrenal insufficiency or congenital adrenal hyperplasia. Low aldosterone, normal cortisol, and high PRA is consistent with aldosterone synthase deficiency (seen in infants with recurrent hypovolemia, failure to thrive).
If your tests show a high level of aldosterone, a low level of renin and a normal cortisol level, your doctor may diagnose you with Conn syndrome or hyperaldosteronism.
Hypoaldosteronism (HA) is a condition marked by decreased synthesis or diminished release of aldosterone (ALD) from the zona glomerulosa of the adrenal glands, or resistance to its action on target tissues.
Hypoaldosteronism is a condition characterized by abnormally low levels or impaired function of aldosterone, a hormone produced by the adrenal glands. Aldosterone plays a vital role in regulating electrolyte balance and blood pressure.
A deficiency of aldosterone, in particular, causes the body to excrete large amounts of sodium and retain potassium, leading to low levels of sodium and high levels of potassium in the blood.
Low aldosterone levels in the presence of high renin activity, often with low sodium, high potassium, is associated with primary hypoaldosteronism. Secondary hypoaldersteronism may be suspected if renin activity is low with low aldosterone concentrations.
If your blood pressure gets too low, ALD signals your kidneys to release more sodium into your blood and to get rid of potassium through urine. This helps keep more water in your bloodstream, which makes your blood pressure increase.
Low aldosterone levels are found in a rare condition called Addison's disease. In Addison's disease, there is a general loss of adrenal function resulting in low blood pressure, lethargy and an increase in potassium levels in the blood (see the article on Addison's disease for further information).