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Elias James Corey (born July 12, 1928) is an American organic chemist. In 1990, he won the Nobel Prize in Chemistry "for his development of the theory and methodology of organic synthesis ", [ 3 ] specifically retrosynthetic analysis .
The first total syntheses of prostaglandin F 2α and prostaglandin E 2 were reported by Elias James Corey in 1969, [9] an achievement for which he was awarded the Japan Prize in 1989. In 1971, it was determined that aspirin -like drugs could inhibit the synthesis of prostaglandins.
Elias James Corey received a Nobel Prize in 1990 for similar achievements, such as the synthesis of gibberellic acid, ginkgolide, and prostaglandins. These pioneering studies laid the foundation for our understanding of natural product chemistry and biochemistry, [162] leading to numerous Nobel Prizes in Chemistry and Physiology or Medicine ...
Elias James Corey Notes Eric Block (born January 25, 1942) is an American chemist whose research has focused on the chemistry of organosulfur and organoselenium compounds , Allium chemistry (the chemistry of garlic , onion , and other alliums), and the chemistry of olfaction .
Corey–Nicolaou macrolactonization is a named reaction of organic chemistry, for the synthesis of lactones from hydroxy acids, found in 1974. [ 1 ] [ 2 ] The reaction uses 2,2'-dipyridyldisulfide and triphenylphosphine as reagents and runs in polar aprotic solvent under mild conditions.
Jason Altom (6 October 1971 – 15 August 1998) was an American PhD student working in the research group of Nobel laureate Elias James Corey at Harvard University. He killed himself by taking potassium cyanide in 1998, citing in his suicide note "abusive research supervisors" as one reason for taking his life. Altom was studying a complex ...
Elias James Corey, organic chemist, emeritus professor of organic chemistry at Harvard University, recipient of the Nobel Prize in Chemistry in 1990 [279] Ruth Schwartz Cowan, historian of science, technology, and medicine, Professor Emerita at the University of Pennsylvania [10]
Considers methods from journals, books, and patent literature from the early 19th century up to the present day and presents important synthetic methods for all classes of compounds. Critically evaluates the preparative applicability and significance of the synthetic methods. Importance: A reference publication. [12]
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