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Perianal cellulitis, also known as perianitis or perianal streptococcal dermatitis, is a bacterial infection affecting the lower layers of the skin around the anus. [1] [2] [3] It presents as bright redness in the skin and can be accompanied by pain, difficulty defecating, itching, and bleeding.
Clindamycin is a lincosamide antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infections), and endocarditis. [5]
The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.
Repeated aspirations of an abscess are preferable in those with multiple abscesses or when the abscess is located in a predominate brain site. Administration of antimicrobials in a high-dose for an extended period of time can offer an alternative treatment strategy in this type of patients and may substitute for surgical evacuation of an abscess.
Management: antibiotics for cellulitis, open and drain wound, saline-soaked packing twice a day, secondary closure. Septic pelvic thrombophlebitis: persistent wide fever swings despite antibiotics, usually normal abdominal or pelvic exams. [19] Management: IV heparin for 7–10 days at rates sufficient to prolong the PTT to double the baseline ...
Being more toxic than the other antibiotic alternatives, it is used only in cases where the Tetracyclines are contraindicated (for example in children). Clindamycin should be given in conjunction with quinine as a 300 mg dose (in adults) four times a day for five days.
Cefazolin, clindamycin, and vancomycin are used to prevent EOD in infants born to penicillin-allergic mothers. [30] [31] Intravenous vancomycin is recommended for IAP in women colonized with a clindamycin-resistant Group B Streptococcus strain and a severe penicillin allergy. [29] [31]
Penicillin G, 5 million units IV initial dose, then 3 million units every 4 hours until delivery or ampicillin, 2 g IV initial dose, then 1 g IV every 4 hours until delivery. [4] [12] [14] Appropriate IAP in GBS colonized women should start as soon as possible once labour starts or the waters have broken. When the first dose is given at least 4 ...