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Benzamide is an organic compound with the chemical formula of C 7 H 7 NO. It is the simplest amide derivative of benzoic acid. In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [5] It is slightly soluble in water, [2] and soluble in many organic solvents. [6]
It was also known as HBI-8000. [2] It is a benzamide HDI and inhibits Class I HDAC1, HDAC2, HDAC3, as well as Class IIb HDAC10. [3] Tucidinostat is approved by the Chinese FDA for relapsed or refractory peripheral T-cell lymphoma (PTCL) and has orphan drug status in Japan.
This page was last edited on 19 December 2023, at 00:04 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
3,4,5-trimethoxy-benzamide. ... C 21 H 28 N 2 O 5: Molar mass: 388.464 g·mol −1: 3D model ... with 2-dimethylaminoethyl chloride affords the ether (2). Reductive ...
Mocetinostat (MGCD0103) is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers including follicular lymphoma, Hodgkin's lymphoma and acute myelogenous leukemia.
Cinitapride (trade names Cintapro, Pemix) is a gastroprokinetic agent and antiemetic agent of the benzamide class which is marketed in India, Mexico, Pakistan and Spain. [1] [2] It acts as an agonist of the 5-HT 1 and 5-HT 4 receptors and as an antagonist of the 5-HT 2 receptors. [3] [4]
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355-02-2 C 7 HF 5 O: pentafluorobenzaldehyde: 653-37-2 C 7 H 3 IN 2 O 3: nitroxynil: 1689-89-0 C 7 H 3 Br 2 NO: bromoxynil: 1689-84-5 C 7 H 4 ClFO 2-chloro-6-fluorobenzaldehyde: 387-45-1 C 7 H 4 ClNO 2: chloroxazone: 95-25-0 C 7 H 4 CrO 3 S: thiophene chromium tricarbonyl: 12078-15-8 C 7 H 4 CrO 3 Se: selenophene chromium tricarbonyl: 12078-16 ...