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The Cologuard Plus test is now approved for adults ages 45 and older who are at average risk for colorectal cancer (CRC). FDA approval was based on findings from the pivotal BLUE-C study, one of ...
Sensitivity measures a test's ability to correctly identify positive results. It is the percentage of patients who were determined by colonoscopy to have pre-cancerous polyps or cancer who had a ...
A positive test is almost always an indication to do a colonoscopy. In most cases the positive result is just due to hemorrhoids ; however, it can also be due to diverticulosis , inflammatory bowel disease ( Crohn's disease , ulcerative colitis ), colon cancer, or polyps .
The dose schedule given every two weeks is as follows: [5] Day 1–2: Oxaliplatin 100 mg/m 2 IV infusion, given as a 120 minutes IV infusion in 500 mL D5W, concurrent with leucovorin 400 mg/m 2 (or levoleucovorin 200 mg/m 2) IV infusion, followed by 5-FU 400 mg/m 2 IV bolus, followed by 46-hour 5-FU infusion (2400 mg/m 2 for first two cycles, and may be increased to 3000 mg/m 2 if tolerated by ...
Exact Sciences Corp. is an American molecular diagnostics company based in Madison, Wisconsin specializing in the detection of early stage cancers. The company's initial focus was on the early detection and prevention of colorectal cancer; in 2014 it launched Cologuard, the first stool DNA test for colorectal cancer.