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PSA was launched in July 1991 by David Hall, owner of the coin grading company Professional Coin Grading Service (PCGS), to serve collectors as a third-party card grader. [1] At the outset, the business faced difficulties owing to a limited demand from collectors who sought card grading services. [ 2 ]
The 4Kscore combines total, free and intact PSA together with human kallikrein 2. [46] It is used to try to determine the risk of a Gleason score greater than 6. [46] The Prostate Health Index (PHI) is a PSA-based blood test for early prostate cancer screening. It may be used to determine when a biopsy is needed.
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
Therefore, in 2014 an international multidisciplinary conference was convened to revise the 2005 system. A 5-point Gleason Grade grouping similar to those such as PI-RADS used with prostate MRI evaluations was proposed to denote prognostically distinct stratification. Grade 1 would indicate the lowest-risk cancer while Grade 5 would indicate ...
Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.Abnormal growth of prostate tissue is usually detected through screening tests, typically blood tests that check for prostate-specific antigen (PSA) levels.
The most appropriate method to use is normally the one where the method is aligned to the end use of the data. For example, to choose whether a chemical compound should be measured by dynamic light scattering or laser diffraction , one generally considers the expected size range, the sample type (liquid or solid), the amount of sample available ...
The PSA prepayment model is a prepayment scale developed by the Public Securities Association in 1985 for analyzing American mortgage-backed securities. The PSA model assumes increasing prepayment rates for the first 30 months after mortgage origination and a constant prepayment rate thereafter. [ 1 ]
The PSA Certified program seeks to address and reduce fragmentation in the IoT product manufacturing and development sectors. It supports the creation of system-on-chips (SoCs) that incorporate a PSA Root of Trust (PSA-RoT), a security component accessible to software platforms and original equipment manufacturers (OEMs).