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Trypanosoma cruzi is a species of parasitic euglenoids. Among the protozoa, the trypanosomes characteristically bore tissue in another organism and feed on blood (primarily) and also lymph. This behaviour causes disease or the likelihood of disease that varies with the organism: Chagas disease in humans, dourine and surra in horses, and a ...
Chagas disease is caused by infection with the protozoan parasite T. cruzi, which is typically introduced into humans through the bite of triatomine bugs, also called "kissing bugs". [4] When the insect defecates at the bite site, motile T. cruzi forms called trypomastigotes enter the bloodstream and invade various host cells. [5]
Triatoma infestans, commonly called winchuka [1] or vinchuca [2] in Argentina, Bolivia, Uruguay and Chile, barbeiro in Brazil, chipo in Venezuela and also known as "kissing bug" or "barber bug" in English, is a blood-sucking bug (like virtually all the members of its subfamily Triatominae) and the most important vector of Trypanosoma cruzi which can lead to Chagas disease.
The subgenus Schizotrypanum contains T. cruzi [13] and a number of bat trypanosomes. The bat species include Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma livingstonei and Trypanosoma wauwau. Other related species include Trypanosoma conorhini and Trypanosoma rangeli. [citation needed]
T. cruzi transmission is carried mainly from human to human by domestic kissing bugs; from the vertebrate to the bug by blood, and from the bug to the vertebrate by the insect's feces, and not by its saliva as occurs in most bloodsucking arthropod vectors such as malaria mosquitoes. [citation needed]
Triatoma is a genus of assassin bug in the subfamily Triatominae (kissing bugs). The members of Triatoma (like all members of Triatominae) are blood-sucking insects that can transmit serious diseases, such as Chagas disease.
The three major human diseases caused by trypanosomatids are; African trypanosomiasis (sleeping sickness, caused by Trypanosoma brucei and transmitted by tsetse flies [3]), South American trypanosomiasis (Chagas disease, caused by T. cruzi and transmitted by triatomine bugs), and leishmaniasis (a set of trypanosomal diseases caused by various species of Leishmania transmitted by sandflies [4]).
Trypanosoma cruzi is the causative agent of Chagas' disease, and as a member of the family Trypanosomatidae, is related to organisms of the genus Phytomonas. [11] In a 2015 study, Phytomonas Jma was tested as a model for the expression of heterologous proteins in the dangerous T. cruzi. [12]