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Phenibut is used in Russia, Ukraine, Belarus and Latvia as a pharmaceutical drug to treat anxiety and to improve sleep (e.g., in the treatment of insomnia). [5] [6] It is also used for various other indications, including the treatment of asthenia, depression, alcoholism, alcohol withdrawal syndrome, post-traumatic stress disorder, stuttering, tics, vestibular disorders, Ménière's disease ...
4-Fluorophenibut (developmental code name CGP-11130; also known as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA) is a GABA B receptor agonist which was never marketed. [1]
In one study, the affinity (K i) values of gabapentinoids for the α 2 δ subunit expressed in rat brain were found to be 0.05 μM for gabapentin, 23 μM for (R)-phenibut, 39 μM for (S)-phenibut, and 156 μM for baclofen. [9] Their affinities (K i) for the GABA B receptor were >1 mM for gabapentin, 92 μM for (R)-phenibut, >1 mM for (S)-phenibut.
The truth is, most things aren't actually all that bad for you if you take them in moderation. Prepare to rejoice and check out the round-up gallery above for 10 supposedly bad things that are ...
Health officials in Europe are investigating Ozempic and the trendy drug’s possible link to an eye-rotting condition that causes blindness. On Dec. 17, the European Medicines Agency announced ...
Olivia Rodrigo‘s music video for “Bad Idea Right?” is on everyone’s mind — and not only because of the not-so cryptic lyrics. The track, which was released on Friday, August 11, is about ...
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Glufimet (dimethyl 3-phenylglutamate hydrochloride) – experimental drug related to phenibut; Glutamic acid (glutamate) – neurotransmitter; Homotaurine (tramiprosate) – GABA A receptor agonist, GABA B receptor antagonist; Hopantenic acid (N-pantoyl-GABA) – central nervous system depressant used in Russia