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[13] [14] Certain morphinan dissociatives such as dextromethorphan are also used in sub-psychoactive dosages to suppress coughing. [15] Ketamine is also currently being studied and is showing promising results as a possible fast-acting antidepressant [16] [17] It may also function as a possible palliative treatment for C-PTSD and chronic pain ...
Dissociative disorders are characterized by distinct brain differences in the activation of various brain regions including the inferior parietal lobe, prefrontal cortex, and limbic system. [16] Those with dissociative disorders have higher activity levels in the prefrontal lobe and a more inhibited limbic system on average than healthy ...
Psychoactive substances that cause temporary dissociation tend to be NMDA receptor antagonists or Κ-opioid receptor agonists. [53] Although, this is not necessarily always the case and dissociation can occur with non-hallucinogenic drugs. [54]
Psychoactive drugs operate by temporarily affecting a person's neurochemistry, which in turn causes changes in a person's mood, cognition, perception and behavior. There are many ways in which psychoactive drugs can affect the brain. Each drug has a specific action on one or more neurotransmitter or neuroreceptor in the brain.
The three main types of dissociative disorders are: Dissociative identity disorder. Once known as multiple personality disorder, dissociative identity disorder usually comes on after extreme abuse ...
To strengthen a single dissociation, a researcher can establish a "double dissociation", a term that was introduced by Hans-Lukas Teuber in 1955. [2] This is the demonstration that two experimental manipulations each have different effects on two dependent variables; if one manipulation affects the first variable and not the second, the other manipulation affects the second variable and not ...
By altering receptor function in one part of the brain, abnormal activity can be induced in other parts of the brain due to the same type of receptor changes. A common example is the effect of D 2 altering drugs (neuroleptics) which can help schizophrenia, but cause a variety of dyskinesias by their action on motor cortex.
There are many ways that one's consciousness can be altered, such as by using psychoactive drugs, which are defined as chemical substances that pass through the blood-brain barrier and disturb brain function, causing changes in awareness, attitude, consciousness, and behavior. [28]