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Orofacial granulomatosis (OFG) is a condition characterized by persistent enlargement of the soft tissues of the mouth, lips and the area around the mouth on the face, causing in most cases extreme pain.
Angular cheilitis may also be associated with orofacial granulomatosis. A related condition is Melkersson–Rosenthal syndrome, a triad of facial palsy, chronic lip edema, and fissured tongue. [29] "Miescher's cheilitis", [30] and "granulomatous macrocheilitis", [31] are synonyms of granulomatous cheilitis.
Melkersson–Rosenthal syndrome is a rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips (usually the upper lip: cheilitis granulomatosis) and the development of folds and furrows in the tongue (fissured tongue). [2]: 799 Onset is in childhood or early adolescence.
Chronic granulomatous disease (Bridges–Good syndrome, chronic granulomatous disorder, Quie syndrome) Common variable immunodeficiency (acquired hypogammaglobulinemia) Complement deficiency; DiGeorge syndrome (DiGeorge anomaly, thymic hypoplasia) Graft-versus-host disease; Griscelli syndrome; Hyper-IgE syndrome (Buckley syndrome, Job syndrome)
Peripheral giant-cell granuloma (PGCG) is an oral pathologic condition that appears in the mouth as an overgrowth of tissue due to irritation or trauma.Because of its overwhelming incidence on the gingiva, the condition is associated with two other diseases, pyogenic granuloma and peripheral ossifying fibroma.
Fissured tongue is seen in Melkersson–Rosenthal syndrome (along with facial nerve paralysis and granulomatous cheilitis).It is also seen in most patients with Down syndrome, in association with geographic tongue, in patients with oral manifestations of psoriasis, and in healthy individuals.
It is called plasma cell gingivitis where the gingiva (gums) are involved, [5] plasma cell cheilitis, [5] where the lips are involved, and other terms such as plasma cell orifacial mucositis, [5] or plasma cell gingivostomatitis where several sites in the mouth are involved. On the lips, the condition appears as sharply outlined, infiltrated ...
"Pulmonary hyalinizing granuloma" is a lesion characterized by keloid-like fibrosis in the lung and is not granulomatous. Similarly, radiologists often use the term granuloma when they see a calcified nodule on X-ray or CT scan of the chest. They make this assumption since granulomas usually contain calcium, although the cells that form a ...