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A comparison of 3 insecticides (selamectin, fipronil, imidacloprid) showed that selamectin reduced larval cat fleas ≥93.5% after 24 h at doses of ≥0.3 μg. In contrast, at 24 h neither fipronil nor imidacloprid reached 90% reduction, even at the highest doses tested (0.5 μg for fipronil and 5.0 μg for imidacloprid).
Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole insecticide class. [3] Fipronil disrupts the insect central nervous system by blocking the ligand-gated ion channel of the GABA A receptor (IRAC group 2B) and glutamate-gated chloride (GluCl) channels. This causes hyperexcitation of contaminated insects' nerves and muscles.
Lentigo in cats is a common dermatological condition characterized by the presence of small, flat, brownish spots on the skin — particularly around the lips, nose, and eyelid margins. Unlike in ...
An important infectious skin disease of cats is ringworm, or dermatophytosis.Other cat skin infections include parasitic diseases like mange and lice infestations.. Other ectoparasites, including fleas and ticks, are not considered directly contagious but are acquired from an environment where other infested hosts have established the parasite's life cycle.
The US Food and Drug Administration (FDA) approved it for flea treatment in dogs in May 2014, [17] and approved the combination fluralaner/moxidectin (Bravecto Plus) as a topical treatment for cats in November 2019.
A single treatment with a topical formulation containing fipronil, (S)-methoprene, eprinomectin and praziquantel was shown to be efficient for the prevention of Otodectes cynotis infestation in cats. Methoprene is able to prevent eggs from hatching and stop mites from maturing; the rest are all parasite-killing drugs. [10]