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A standard ultracentrifuge by manufacturer Beckman Coulter. An ultracentrifuge is a centrifuge optimized for spinning a rotor at very high speeds, capable of generating acceleration as high as 1 000 000 g (approx. 9 800 km/s²). [1] There are two kinds of ultracentrifuges, the preparative and the analytical ultracentrifuge.
A large laboratory centrifuge from Beckman. Beckman Coulter, Inc. is a Danaher Corporation company that develops, manufactures, and markets products relevant to biomedical testing. It operates in the industries of diagnostics and life sciences. The company was established in 1935 as National Technical Laboratories, and has become an ...
In centrifugation the clearing factor or k factor represents the relative pelleting efficiency of a given centrifuge rotor at maximum rotation speed. It can be used to estimate the time t {\displaystyle t} (in hours) required for sedimentation of a fraction with a known sedimentation coefficient s {\displaystyle s} (in svedbergs ):
Beckman Coulter (now Danaher) has previously manufactured chain termination and capillary electrophoresis-based DNA sequencers under the model name CEQ, including the CEQ 8000. [27] The company now produces the GeXP Genetic Analysis System, which uses dye terminator sequencing. [28]
Arnold Orville Beckman (April 10, 1900 – May 18, 2004) was an American chemist, inventor, investor, and philanthropist. While a professor at California Institute of Technology, he founded Beckman Instruments based on his 1934 invention of the pH meter, a device for measuring acidity (and alkalinity), later considered to have "revolutionized the study of chemistry and biology". [1]
Density gradients for purifying cells are also run in these centrifuges. Swinging-bucket rotors tend to be used very widely because of the huge flexibility of sample size through the use of adaptors. [9] These machines have maximum rotor speeds of less than 10 000 rpm and vary from small, bench-top to large, floor-standing centrifuges. [11]
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