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Color dilution alopecia is caused by a dilution gene affecting eumelanin. It is an inherited type of follicular dysplasia. It is an inherited type of follicular dysplasia. It most commonly affects dogs with blue or fawn coats , which are dilutions of black and brown, respectively Dilution is caused by irregularities in melanin transfer and storage.
Great Danes also may carry the merle gene, which is part of the genetic makeup that creates the harlequin coloring. [37] The merle gene is an incomplete dominant, meaning only one copy of the gene is needed to show the merle coloring; two merle genes produce excessive white markings and many health issues such as deafness, blindness, or other ...
Often mistaken for a "double merle", a harlequin merle (or just harlequin), is a Great Dane that carries both the merle pattern allele and the co-dominant modifying gene for harlequin, PSMB7 (also known as H). This causes most or all of the diluted "blue" color to be replaced with white, resulting in a dog that is mostly white with black patches.
It is especially true for a girl named Bella and her Great Dane, George. At just 11 years old, Bella's growth has been stunted due to a rare genetic disorder called Morquio Syndrome, ...
Mantle (climbing), the external covering of a climbing rope. Mantle, a black and white dog coat colour, especially in Great Danes; Mantle (mollusc), a layer of tissue in molluscs which secretes the shell; Fireplace mantle or mantel, the hood over the grate of a fire; Gas mantle, a device for generating bright white light when heated by a flame
Image credits: Leanador Being one of the world’s biggest dog breeds, Great Danes are truly mesmerizing and quite unique animals.One of the biggest factors that makes them stand out so much is ...
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Research indicates that the majority of variation in coat growth pattern, length and curl can be attributed to mutations in four genes, the R-spondin-2 gene or RSPO2, the fibroblast growth factor-5 gene or FGF5, the keratin-71 gene or KRT71 [15] and the melanocortin 5 receptor gene (MC5R). The wild-type coat in dogs is short, double and straight.