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Dupuytren's contracture of the right little finger. Arrow marks the area of scarring. Typically, Dupuytren's contracture first presents as a thickening or nodule in the palm, which initially can be with or without pain. [12] Later in the disease process, which can be years later, [13] there is increasing loss of range of motion of the affected ...
Guillaume Dupuytren, Baron Dupuytren (UK: / ˌ dj uː p w iː ˈ t r æ̃, dj uː ˈ p w iː t r ɛ n /, [1] US: / d ə p w iː ˈ t r æ̃, d ə ˈ p w iː t r ən /, [2] French: [ɡijom dypɥitʁɛ̃]; 5 October 1777 – 8 February 1835) was a French anatomist and military surgeon.
Many of these deformities, such as Dupuytren's contracture, swan-neck deformity etc. can be associated with both a chronic, progressive event, or an acute injury; [17] such as boutonnière deformity, which can be caused by trauma, [1] or induced by a chronic condition like rheumatoid arthritis. [20]
The term fibromatosis refers to a group of soft tissue tumors [1] which have certain characteristics in common, including absence of cytologic and clinical malignant features, a histology consistent with proliferation of well-differentiated fibroblasts, an infiltrative growth pattern, and aggressive clinical behavior with frequent local recurrence.
In adjunct with surgery, refractory muscle contracture can also be treated with Botulinum toxins A and B; however, the effectiveness of the toxin is slowly lost over time, and most patients need a single treatment to correct muscle contracture over the first few weeks after surgery. [21] Shortening of the surgically lengthened muscle can re-occur.
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