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Zinc and vitamin D are also essential for bone health but have the added benefit for men over 50 by reducing the risk of erectile dysfunction, a condition commonly affecting men over age 40 ...
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Vitamin D (the inactive version) is mainly from two forms: vitamin D 3 and vitamin D 2.Vitamin D 3, or cholecalciferol, is formed in the skin after exposure to sunlight or ultra violet radiation or from D 3 supplements or fortified food sources.
Ergocalciferol is available as a generic medication and over the counter. [6] In 2022, it was the 38th most commonly prescribed medication in the United States, with more than 15 million prescriptions. [10] [11] Certain foods such as breakfast cereal and margarine have ergocalciferol added to them in some countries.
Previtamin D 3 is an intermediate in the production of cholecalciferol (vitamin D 3).. It is formed by the action of UV light, most specifically UVB light of wavelengths between 295 and 300 nm, acting on 7-dehydrocholesterol in the epidermal layers of the skin.
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LD 50 of 4.4 mg/kg has been reported in rabbits, with lethality to almost all rabbits ingesting doses greater than 15 mg/kg. [54] Toxicity has been reported across a wide range of cholecalciferol dosages, with LD 50 as high as 88 mg/kg or LD Lo as low as 2 mg/kg reported for dogs. [55]
Under normal circumstances, ample quantities of 7-dehydrocholesterol (about 25–50 μg/cm 2 of skin) are available in the stratum spinosum and stratum basale of human skin to meet the body's vitamin D requirements. 7-DHC insufficiency has been proposed as an alternate cause for Vitamin D deficiency.