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Bacteria in the human gut’s intestines are the most diverse in the human body and play a vital role in human health. In the gastrointestinal tract, dysbiosis manifests particularly during small intestinal bacterial overgrowth (SIBO), commonly caused by a decrease in the passage of food and waste through the gastrointestinal tract following surgery or other pre-existing conditions. [17]
Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...
The species and diversity of the microorganisms may be related to the various levels of hormones during pregnancy. Vaginal flora can be transmitted to babies during birth. Vaginal dysbiosis can lead to vaginal infections like bacterial vaginosis which makes one relatively susceptible to sexually transmitted diseases.
The gut microbiota is important for maintaining homeostasis in the intestine. Development of intestinal cancer is associated with an imbalance in the natural microflora (dysbiosis). [118] The secondary bile acid deoxycholic acid is associated with alterations of the microbial community that lead to increased intestinal carcinogenesis. [118]
The project was designed with the aim of countering that misconception that bacteria are always harmful to humans [20] and that humans are at war with bacteria. [21] In actuality, most strains of bacteria are harmless [13] if not beneficial for the human body. [22] Another of the project's goals is to foster public interest in microbiology. [17]
The cause of IBS is not known but multiple factors have been proposed to lead to the condition. [2] Theories include combinations of " gut–brain axis " problems, alterations in gut motility , visceral hypersensitivity, infections including small intestinal bacterial overgrowth , neurotransmitters , genetic factors, and food sensitivity . [ 2 ]