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The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. [3] [4] [5] Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk.
The main risk factor is a history of diabetes mellitus type 2. [4] Occasionally it may occur in those without a prior history of diabetes or those with diabetes mellitus type 1. [3] [4] Triggers include infections, stroke, trauma, certain medications, and heart attacks. [4] Other risk factors: Lack of sufficient insulin (but enough to prevent ...
The risk of infection is increased with traumatic injury to the skin and also in people with certain underlying conditions such as diabetes, chronic venous insufficiency and immunosuppression. [3] Staphylococcal and Streptococcal organisms remain the most common causes of superficial infection after a flooding event. [4]
Nonfreezing cold injury commonly affects the feet due to prolonged exposure to wet socks or cold standing water. [4] Symptoms progress through a series of four stages. [4] [15] A severe case of trench foot. During cold exposure. Affected skin becomes numb, which can cause a clumsy walking pattern if the feet are affected
Diabetic foot ulcer is a breakdown of the skin and sometimes deeper tissues of the foot that leads to sore formation. It is thought to occur due to abnormal pressure or mechanical stress chronically applied to the foot, usually with concomitant predisposing conditions such as peripheral sensory neuropathy, peripheral motor neuropathy, autonomic neuropathy or peripheral arterial disease. [1]
The most frequent cause of hospitalization for diabetic patients is due to foot infections. [3] Symptoms may include pus from a wound, redness, swelling, pain, warmth, tachycardia, or tachypnea. [4] Complications can include infection of the bone, tissue death, amputation, or sepsis. [2] They are common and occur equally frequently in males and ...
The cause is unknown but is thought to be associated with diabetic neuropathy and vascular complications; because the lesions are more common on the shins, some suggest it represents an altered response to injury. It is seen more commonly in patients with longstanding diabetes and poor glucose control.
The pathological mechanism by which frostbite causes body tissue injury can be characterized by four stages: Prefreeze, freeze-thaw, vascular stasis, and the late ischemic stage. [16] Prefreeze phase: involves the cooling of tissues without ice crystal formation. [16] Freeze-thaw phase: ice-crystals form, resulting in cellular damage and death ...