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[58] [45] [68] In the case of the sulfate salt, its generic name is ephedrine sulfate or ephedrine sulphate and the former is its USAN Tooltip United States Adopted Name while the latter is its BANM Tooltip British Approved Name. [58] [45] [68] A synonym of ephedrine sulfate is isofedrol. [58] These names all refer to the (1R,2R)-enantiomer of ...
The elimination half-life of pseudoephedrine on average is 5.4 hours [2] and ranges from 3 to 16 hours depending on urinary pH. [1] [11] At a pH of 5.6 to 6.0, the elimination half-life of pseudoephedrine was 5.2 to 8.0 hours. [11]
The Ephedra alkaloids, ephedrine and pseudoephedrine – constituents of E. sinica and other members of the genus – have sympathomimetic and decongestant qualities, [22] and have been used as dietary supplements, mainly for weight loss. [23] The drug ephedrine is used to prevent low blood pressure during spinal anesthesia. [22]
A wide variety of alkaloid and non-alkaloid compounds have been identified in various species of Ephedra.Of the six ephedrine-type ingredients found in ephedra (at concentrations of 0.02-3.4%), the most common are ephedrine and pseudoephedrine, [13] which are the sources of its stimulant and thermogenic effects. [4]
Ephedra was used 5000 years ago in China as a medicinal plant; its active ingredients are alkaloids ephedrine, pseudoephedrine, norephedrine (phenylpropanolamine) and norpseudoephedrine . Natives of Yemen and Ethiopia have a long tradition of chewing khat leaves to achieve a stimulating effect.
Ephedrine. Ephedrine, a stereoisomer of pseudoephedrine, acts as a direct and indirect sympathomimetic amine. Its indirect mechanism makes it more unique than other sympathomimetic agents, for example, pseudoephedrine and phenylephrine. [9] It directly binds to both alpha and beta receptors.
English: This is the molecular structure of pseudoephedrine presented in a way which makes it easy to compare to the image currently displayed on the page for ephedrine. Date 28 October 2018
Other ephedrine-related compounds produce a blue to greenish-blue precipitate. This precipitate could be seen as characteristic for the members of the ephedrine group other than pseudoephedrine and ephedrine itself, hence, the Chen-Kao test appears to show a significant specificity within the ephedrine group.