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The hamster zona-free ovum test (HZFO test), or hamster egg-penetration test, or sometimes just hamster test, is an in-vitro test used to study physiological profile of spermatozoa. [1] The primary application of the test is to diagnose male infertility caused by sperm unable to penetrate the ova .
In some cases the hamster zona-free ovum test may also be used to diagnose fertility. Genetic testing and chromosomal analysis can rule out some other causes of male infertility, such as Klinefelter syndrome. A recent study identified epigenetic patterns in male sperm that may contribute to infertility. [21]
The male infertility crisis is an increase in male infertility since the mid-1970s. [91] The issue attracted media attention after a 2017 meta-analysis found that sperm counts in Western countries had declined by 52.4 percent between 1973 and 2011.
Men open up about experiencing male infertility. (Image: Getty; designed by Quinn Lemmers) (Design by Quinn Lemmers for Yahoo / Photo: Getty Images)
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For the male, semen collection is a standard diagnostic test to ascertain problems with the semen quality, while females may undergo a number of tests including an ovulation analysis, x-ray of fallopian tubes and uterus, and laparoscopy. [1] They may also perform ultrasounds by a sonographer and advanced pregnancy tests.
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