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Due to the causal relationship of insufficient zinc levels to taste disorders, research has been conducted to test the efficacy of zinc supplementation as a possible treatment for dysgeusia. In a randomized clinical trial, fifty patients with idiopathic dysgeusia were given either zinc or a lactose placebo. [9]
Zinc deficiency is defined either as insufficient zinc to meet the needs of the body, or as a serum zinc level below the normal range. However, since a decrease in the serum concentration is only detectable after long-term or severe depletion, serum zinc is not a reliable biomarker for zinc status. [1]
While zinc supplementation may treat certain taste dysfunctions, there is a lack of evidence for treatment regarding hypogeusia and dysgeusia not caused by low zinc concentrations in the body. [6] While the mechanisms surrounding hypogeusia from PD are hypothesized, specific treatments are not researched enough. [ 3 ]
Acrodermatitis enteropathica is an autosomal recessive metabolic disorder affecting the uptake of zinc through the inner lining of the bowel, the mucous membrane.It is characterized by inflammation of the skin around bodily openings (periorificial) and the tips of fingers and toes (acral), hair loss (), and diarrhea.
Mineral deficiency is a lack of the dietary minerals, the micronutrients that are needed for an organism's proper health. [1] The cause may be a poor diet, impaired uptake of the minerals that are consumed, or a dysfunction in the organism's use of the mineral after it is absorbed.
Ageusia (from negative prefix a-and Ancient Greek γεῦσις geûsis 'taste') is the loss of taste functions of the tongue, particularly the inability to detect sweetness, sourness, bitterness, saltiness, and umami (meaning 'savory taste'). It is sometimes confused with anosmia – a loss of the sense of smell.
Possibly subjective xerostomia, dysgeusia (altered taste), thirst, headaches, chronic back pain, irritable bowel syndrome, dysmenorrhea, globus pharyngis, anxiety, decreased appetite, depression and personality disorders: Time course: Type 2 (most common) pain upon waking and throughout day, less commonly other patterns. Exacerbating/Relieving ...
Zinc gluconate is a popular form for the delivery of zinc as a dietary supplement providing 14.35% elemental zinc by weight. Gluconic acid is found naturally, and is industrially made by the fermentation of glucose , typically by Aspergillus niger , but also by other fungi , e.g. Penicillium , or by bacteria , e.g. Acetobacter , Pseudomonas and ...