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Henley Street Bridge over the Tennessee River: Main Street (east)/Cumberland Avenue (west) - University of Tennessee, West Knoxville: Former southern end of US 11/US 70/SR 1 concurrency: I-40 / I-275 – Nashville, Asheville, NC, Lexington, KY: I-40 exit 388; I-275 exit 0A: SR 62 west (Western Avenue) – Karns, Oak Ridge: Eastern terminus of SR 62
Interstate 26. Connecting directly from I-81, I-26 offers another major corridor for travel between East Tennessee and the Carolinas. Motorists can use this route to travel south from I-81 toward ...
U.S. Route 321 (US 321) is a spur of U.S. Route 21. It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with both serving as southern termini. It reaches its northernmost point at Elizabethton, Tennessee, just northeast of Johnson City.
U.S. Route 25 or U.S. Highway 25 (US 25) is a north–south United States Numbered Highway that runs for 750 miles (1,210 km) in the Southern and Midwestern U.S. Its southern terminus is in Brunswick, Georgia, from where it proceeds mostly due north, passing through the cities of Augusta, Georgia; Greenville, South Carolina; and Asheville, North Carolina, before dividing into two branches ...
I-81 roughly follows the corridors of U.S. Routes 11E and 11W in Tennessee, but unlike many stretches of Interstate Highways, does not closely parallel any U.S. Numbered Highway until it reaches Bristol. The first parts of I-81 in the state were constructed in the early 1960s, with additional progress made on the Interstate throughout that decade.
I-75 enters Tennessee on the eastern side of East Ridge, a southern suburb of Chattanooga. Less than 0.5 miles (0.80 km) into Tennessee is an interchange with US 41 (unsigned US 76). About a mile (1.6 km) later, at exit 2, is a three-way interchange with the eastern terminus of I-24, which runs west into downtown Chattanooga and to Nashville ...