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  2. Langerhans cell histiocytosis - Wikipedia

    en.wikipedia.org/wiki/Langerhans_cell_histiocytosis

    In non-tumourous lesions, there is a symmetrical hyperintense T2 signal with hypointense or hyperintense T1 signal extending from grey matter into the white matter. In the basal ganglia, MRI shows a hyperintense T1 signal in the globus pallidus. [36] Assessment of endocrine function and bone marrow biopsy are also performed when indicated. [37]

  3. Biomarkers of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Biomarkers_of_multiple...

    Diffusivity can be more accurate. Distinct patterns of diffusivity in MS lesions suggest that axonal loss dominates in the T1 hypointense core and that the effects of de/remyelination may be better detected in the "T2-rim", where there is relative preservation of structural integrity. [14]

  4. Fluid-attenuated inversion recovery - Wikipedia

    en.wikipedia.org/wiki/Fluid-attenuated_inversion...

    In the case of CSF suppression, one aims for T 1-weighted images, which prioritize the signal of fat over that of water. Therefore, if the long TI (inversion time) is adjusted to a zero crossing point for water (none of its signal is visible), the signal of the CSF is theoretically being "erased," from the derived image.

  5. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Pathology_of_multiple...

    First of all, there is a diffuse axon degeneration, probably related to the NAWM appearance. Later, there is a second axonal damage mechanism localized in old demyelinating lesions, probably produced by B-Cells. This second damage is related to the T1-Hypointense lesions (MRI black holes) which appear when a demyelinating lesion is not ...

  6. Tumefactive multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Tumefactive_multiple_sclerosis

    Using T2-weighted imaging, the lesions appear with high signal intensity, meaning that the lesions appear white and brighter than the rest of the brain. When T1-weighted imaging is contrast-enhanced through the addition of gadolinium, the open ring enhancement can be viewed as a white ring around the lesion. [ 40 ]

  7. MRI pulse sequence - Wikipedia

    en.wikipedia.org/wiki/MRI_pulse_sequence

    To create a T1-weighted image, magnetization is allowed to recover before measuring the MR signal by changing the repetition time (TR). This image weighting is useful for assessing the cerebral cortex, identifying fatty tissue, characterizing focal liver lesions, and in general, obtaining morphological information, as well as for post-contrast ...

  8. Bone marrow - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow

    Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a person weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow. [5] Human marrow produces approximately 500 billion blood cells per day, which join the systemic circulation via permeable vasculature sinusoids within the medullary ...

  9. T2*-weighted imaging - Wikipedia

    en.wikipedia.org/wiki/T2*-weighted_imaging

    T2*-weighted imaging of the brain 26 weeks after subarachnoid hemorrhage, showing hemosiderin deposits as hypointense areas. [1] T 2 *-weighted imaging is an MRI sequence to quantify observable or effective T 2 (T2* or "T2-star"). In this sequence, hemorrhages and hemosiderin deposits become hypointense. [2]