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In the early days of insulin treatment for type 1 diabetes there was much debate as to whether strict control of hyperglycaemia would delay or prevent the long-term complications of diabetes. The work of Pirart [50] suggested that microvascular complications of diabetes were less likely to occur in individuals with better glycaemic control.
The study focused on metformin and GLP-1 drugs, including semaglutide, tirzepatide and liraglutide. Among nearly 13,000 individuals with both diabetes and asthma, metformin lowered the risk of asthma attacks by 30%, and adding a GLP-1 drug further reduced it by 40%. [121]
A new study compares the benefits and risks of taking GLP-1 medications for weight loss, including risks of dementia, addiction, heart disease, and gastrointestinal problems, among others.
The 2022 American Diabetes Association (ADA) standards of medical care in diabetes include GLP-1 agonists or SGLT2 inhibitors as a first-line pharmacological therapy for type 2 diabetes in patients who have or are at high risk for atherosclerotic cardiovascular disease or heart failure. They are also a first-line treatment for people with both ...
GLP-1 drugs like Ozempic, Mounjaro, Wegovy, and Zepbound are powerful tools for treating diabetes and aiding with weight loss, but a new study suggests these medications could also help prevent ...
Dulaglutide, sold under the brand name Trulicity among others, [8] is a medication used for the treatment of type 2 diabetes in combination with diet and exercise. [9] [10] It is also approved in the United States for the reduction of major adverse cardiovascular events in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors.
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