Search results
Results From The WOW.Com Content Network
Bubaline alphaherpesvirus 1 (BuHV-1) is a species of virus in the genus Varicellovirus, subfamily Alphaherpesvirinae, family Herpesviridae, and order Herpesvirales.
It is very common and contagious; about 67% of the world population under the age of 50 has Herpes simplex virus 1. [5] It is often acquired orally during childhood. It may also be sexually transmitted, including contact with saliva, such as kissing and mouth-to-genital contact ( oral sex ). [ 6 ]
(1) nucleoprotein, (2) DNA, (3) capsid, (4) tegument, (5) envelope, (6) glycoprotein. Click to enlarge. Electron micrograph of various viruses from the Orthoherpesviridae family including Human alphaherpesvirus 3 ( Chickenpox ), Human alphaherpesvirus 1 , and Human alphaherpesvirus 2
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. [1] [2] Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus.
It is estimated to affect at least 1 in 500,000 individuals per year, [1] and some studies suggest an incidence rate of 5.9 cases per 100,000 live births. [ 2 ] About 90% of cases of herpes encephalitis are caused by herpes simplex virus-1 (HSV-1), the same virus that causes cold sores .
However, tumour cells have much weaker PKR-linked defences, which may be the reason why HSV1716 effectively kills a wide range of tumour cell lines in tissue culture. An HSV1716 variant, HSV1716NTR is an oncolytic virus generated by inserting the enzyme NTR into the virus HSV1716 as a GDEPT strategy. [ 4 ]
[11] [13] These "targets" should generally be as unlike any proteins or parts of proteins in humans as possible, to reduce the likelihood of side effects and toxicity. [8] The targets should also be common across many strains of a virus, or even among different species of virus in the same family, so a single drug will have broad effectiveness.
The virus Psittacid alphaherpesvirus 1 is the etiologic agent that causes Pacheco's disease. This virus species is closely related to Gallid alphaherpesvirus 1. [2] It was initially identified as a herpesvirus by examining its virion size, sensitivity to ether, the formation of intranuclear inclusions, its ability to thicken the nuclear membranes of the host cells.