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Biotin is a popular nutritional supplement. There are recommendations that horses need 15 to 25 mg/day. Studies report biotin improves the growth of new hoof horn rather than improving the status of existing hoof, so months of supplementation are needed for the hoof wall to be completely replaced. [61]
Natural hoof supplements can be used as a boost to the immune systems of horses when concerned with laminitis or other hoof ailments. D-Biotin supplements, often including the sulfur-containing amino acid dl-Methionine, are commonly known supplements that may be helpful for managing hoof health if they're deficient/imbalanced in the diet. [14] [15]
The average modern horse on good hay or pasture with light work usually does not need supplements; however, horses subjected to stress due to age, intensive athletic work, or reproduction may need additional nutrition. [27] Extra fat and protein are sometimes added to the horse's diet, along with vitamin and mineral supplements. [19]
Biotin deficiency is a relatively uncommon condition, and the vast majority of people can get enough biotin (also known as vitamin B7) just from eating a well-rounded, balanced diet, per Healthline.
The tetrameric protein contains four identical subunits (homotetramer), each of which can bind to biotin (Vitamin B 7, vitamin H) with a high degree of affinity and specificity. The dissociation constant of the avidin-biotin complex is measured to be K D ≈ 10 −15 M, making it one of the strongest known non-covalent bonds. [2]
The treatment of equine lameness is a complex subject. Lameness in horses has a variety of causes, and treatment must be tailored to the type and degree of injury, as well as the financial capabilities of the owner. Treatment may be applied locally, systemically, or intralesionally, and the strategy for treatment may change as healing progresses.