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  2. Antigen-presenting cell - Wikipedia

    en.wikipedia.org/wiki/Antigen-presenting_cell

    Antigen-presenting cell. Antigen presentation stimulates immature T cells to become either mature "cytotoxic" CD8+ cells or mature "helper" CD4 + cells. An antigen-presenting cell (APC) or accessory cell is a cell that displays an antigen bound by major histocompatibility complex (MHC) proteins on its surface; this process is known as antigen ...

  3. Lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Lymphocyte

    A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...

  4. Immune system - Wikipedia

    en.wikipedia.org/wiki/Immune_system

    The cells of the adaptive immune system are special types of leukocytes, called lymphocytes. B cells and T cells are the major types of lymphocytes and are derived from hematopoietic stem cells in the bone marrow. [57] B cells are involved in the humoral immune response, whereas T cells are involved in cell-mediated immune response.

  5. Antigen presentation - Wikipedia

    en.wikipedia.org/wiki/Antigen_presentation

    Antigen presentation. Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells. Antigen presentation is a vital immune process that is essential for T cell immune response triggering. Because T cells recognize only fragmented antigens displayed on cell surfaces, antigen processing must occur before ...

  6. Adaptive immune system - Wikipedia

    en.wikipedia.org/wiki/Adaptive_immune_system

    B cells play a large role in the humoral immune response, whereas T cells are intimately involved in cell-mediated immune responses. In all vertebrates except Agnatha, B cells and T cells are produced by stem cells in the bone marrow. [6] T cell progenitors then migrate from the bone marrow to the thymus, where they develop further.

  7. T cell - Wikipedia

    en.wikipedia.org/wiki/T_cell

    Contents. T cell. T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, [ 1 ] found in the bone ...

  8. Co-stimulation - Wikipedia

    en.wikipedia.org/wiki/Co-stimulation

    Co-stimulation. Co-stimulation is a secondary signal which immune cells rely on to activate an immune response in the presence of an antigen -presenting cell. [1] In the case of T cells, two stimuli are required to fully activate their immune response. During the activation of lymphocytes, co-stimulation is often crucial to the development of ...

  9. Immune receptor - Wikipedia

    en.wikipedia.org/wiki/Immune_receptor

    Allow phagocytic and B cells to recognize microbes and immune complexes Fc receptors: Epitope-antibody complexes: Stimulate phagocytosis: B cell receptors: Epitopes: B cell differentiation into plasma cells and proliferation T cell receptors: Linear epitopes bound to MHC: Activate T cells: Cytokine receptors: Cytokines: Regulation and co ...