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Ibuprofen, an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen .
Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. [10] Ibuprofen was discovered in 1961 by Stewart Adams and John Nicholson [12] while working at Boots UK Limited and initially marketed as Brufen. [13] It is available under a number of brand names, including Advil, Motrin, and Nurofen.
Ibuprofen/paracetamol. Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9][10][11]
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Hydrocodone/ibuprofen (INNs), sold under the brand name Vicoprofen, is a fixed-dose combination analgesic medication used in short-term therapy to relieve severe pain. [3][4] Vicoprofen combines the analgesic and antitussive properties of hydrocodone with the analgesic, anti-inflammatory, and antipyretic properties of ibuprofen. [1]
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Nurofen Plus is a pain relief medication based on codeine and ibuprofen. [7] It contains 12.8 mg of codeine phosphate (a mild opioid analgesic) and 200 mg of ibuprofen, [7] which is an NSAID. Nurofen Plus is the only product in the Nurofen range that contains codeine. The original Nurofen Plus tablet was manufactured in two equal parts, joined ...
The brand first entered the American market in 1984 through Whitehall [3] (itself a division of Wyeth, which was purchased by Pfizer in 2009), [4] the same year Ibuprofen gained Food and Drug Administration approval for over-the-counter sales in the United States (being available via prescription since 1974). [5]